[Journal Club] Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naive and Treated Crohn’s Disease
Inflammatory Bowel Diseases 2022 Sushma Chowdary Maddipatla, Vasantha L. Kolachala, Suresh Venkateswaran, Peng Qiu and Subra Kugathasan Summary 연구 필요성 Crohn’s disease shows considerable heterogeneity in disease progression and treatment response. Bulk transcriptomic studies cannot resolve cell type-specific changes, necessitating single-cell approaches to better understand disease mechanisms. 연구 목적 To characterize cellular composition and transcriptional […]